Illustrated Glossary of Organic Chemistry
S
N
Ar
mechanism
:
An
aromatic
substitution
mechanism
featuring
nucleophilic addition
to an
aromatic
ring (which destroys the ring's
aromaticity
), followed by an
elimination
step (which restores the lost
aromaticity
).
This S
N
Ar reaction begins with
nucleophilic addition
of
methoxide
ion
(
-
OCH
3
; a
nucleophile
) to the
benzene ring
(the
addition
step), followed by
elimination
of fluoride
ion
(a
leaving group
) to give the final
product
.
Related terms:
Electrophilic aromatic substitution
,
EAS
,
benzyne
,
S
N
1 mechanism
,
S
N
2 mechanism
,
E2 mechanism
,
E1 mechanism
,
E1
cb
mechanism
,
Chichibabin reaction
,
Sanger's reagent
Wikipedia entry
Return to glossary index