Announcements

1. Make sure that you make progress on your formal report as well in terms of literature search and writing the parts that you completed already in the lab. The draft version of paper is due on 2-1-2008 at 5 pm. The draft version is worth 15 points, the final paper 45 points. For more information what the draft is supposed to contain see here. Late submission will receive less credit. The more of your work you submit here, the more feedback you will get, which will beneficial for the final version. We will try to return the reports by Monday.

2. The second quiz will be administered on Tuesday, January 22, 2008 at 12 pm covering the resolution step and the ligand synthesis. Please make sure that you show up on time. Otherwise you will not be allowed to take the quiz.

ATTN: Answers to the below questions are due at the start of your lab period; these answers should be part of your pre-lab write-up.

1. Referring to the synthesis and characterization of the Jacobsen catalyst, answer the following questions.

a. In the initial stage of the reaction the suspension of the ligand and the Mn(OAc)₂*4 H₂O is refluxed. Explain why and what observation will the student usually make? Show pertinent chemical equations.

b. How is the oxidant introduced into the system? What does the student have to keep in mind here?

c. Why is the reaction monitored with TLC? What is used as mobile phase?

d. Why is dichloromethane used during the workup?

e. After extraction with water and sat. sodium chloride solution, heptane added to the solution. The mixture is then gently heated. How does the student know that he heated long enough?

f. How can one rationalize this difference in C=N stretching frequencies in the ligand and the catalyst?

g. Why do we neither acquire the optical rotation nor the ¹H-NMR spectrum for the catalyst?