Announcements

1. Make sure that you make progress on your formal report as well in terms of literature search and writing the parts that you completed already in the lab.

2. The next will be administered on Tuesday January 24, 2006 at 12 pm. The material covered will mainly include the ligand and the resolution step.Please make sure that you show up on time.

3. The draft version of paper is due on 2-3-2005 at 5 pm. The draft version is worth 15 points, the final paper 45 points. For more information what the draft is supposed to contain see here. Late submission will receive less credit. The more of your work you submit here, the more feedback you will get, which will beneficial for the final version. We will try to return the reports by Monday.

ATTN: Answers to the below questions are due at the start of your lab period; these answers should be part of your pre-lab write-up.

1. Referring to the synthesis and characterization of the Jacobsen catalyst, answer the following questions.

a. In some cases the solution starts to turn brown immediately after the Mn(OAc)₂ was added, in other cases only after the introduction of air. Explain briefly why and show pertinent equations.

b. How can the reaction time for this reaction be optimized?

c. Why is heptane added during the workup? Could pentane be used instead?

d. The stretching frequency of the C=N bond in the catalyst is shifted by ~20 cm^-1 to lower wavenumbers. Rationalize this observation.

e. A student plans to acquire the UV-Vis spectrum for the catalyst in the range from 200-700 nm. Determine the appropriate concentration.

2. To a certain degree the catalyst works similar compared to cytochrome P₄₅₀. Explain briefly.