Solvent

Formula

m.p. (oC)

b.p. (oC)

Density (g/cm3)

Dielectric Constant

tan δ

Log Kow

eo(SiO2)

 eo (Al2O3)

η(cp)
(20 oC)

P

UV Cutoff
nm

Solubility in water

Health hazards

Acetic Acid

CH3COOH

  17

118

1.049

6.2

0.174

-0.17

>0.73

large

 1.25

6.2

260

Corr.

Acetone

CH3(C=O)CH3

-95

  56

0.790

21.01

0.054

-0.24

0.47

0.56

0.32

5.1

330

 

Acetonitrile

CH3C≡N

-48

  81

0.786

36.64

0.062

-0.34

0.50

0.65

0.37

5.8

190

 

Benzene

C6H6

   5

  80

0.874

2.28

 

 2.13

0.25

0.32

0.65

3

280

0.0720

C, M, T

Carbon disulfide

CS2

-23

  77

1.263

2.64

 

 1.84

0.14

0.15

0.36

 

380

0.20

C, M, T

Carbon tetrachloride

CCl4

-23

  77

1.594

2.24

 

 2.83

0.14

0.18

0.97

1.6

265

0.0820

C, M, T

Chloroform

CHCl3

-64

  62

1.483

4.81

0.091

 1.97

0.26

0.40

0.57

4.1

245

0.8220

C, M, T

Cyclohexane

C6H12

   7

  81

0.779

2.02

 

 3.44

-0.05

0.04

0.98

0.2

210

 

M, T?

1,2-Dichloroethane

C2H4Cl2

-35

  84

1.235

10.36

0.127

 1.48

0.32

0.42

0.79

3.7

230

0.8720

C, M, T

Dichloromethane

CH2Cl2

-95

  40

1.327

8.93

0.042

 1.25

0.32

0.42

0.44

3.1

235

220

C, M, T

Diethyl ether

CH3CH2OCH2CH3

-116

  36

0.714

4.27

 

 0.89

0.38

0.38

0.22

2.8

218

7.520

M, T

1,2-Dimethoxyethane

CH3OCH2CH2OCH3

-58

  84

0.863

7.20

 

-0.21

 

 

0.42

 

220

M, T

Dimethylsulfoxide

CH3(S=O)CH3

  18

189

1.101

47.24

0.825

-1.35

0.41

0.62

2.24

7.2

265

M?

1,4-Dioxane

C4H8O2

  12

101

1.034

2.22

 

-0.27

0.49

0.56

1.54

4.8

215

M, T

Ethanol

CH3CH2OH

-114

  78

0.789

25.3

0.941

-0.24

0.65

0.88

1.20

5.2

210

M, T

Ethyl acetate

CH3COOCH2CH3

-84

  78

  0.900

6.08

0.059

 0.73

0.38

0.58

0.46

4.3

255

8.520

M

Hexane

C6H14

-95

  69

0.655

1.88

0.020

 3.90

0

0

0.31

0.01

195

 

M, T?

Isopropanol

(CH3)2CHOH

-90

  82

0.785

20.2

0.799

 0.05

0.63

0.82

2.35

4.3

210

T

Methanol

CH3OH

-98

  65

0.791

33

0.659

-0.77

0.73

0.95

0.60

5.1

210

T

Methylethyl ketone

C4H8O

-86

  80

0.805

18.51

0.079

 0.29

0.39

0.51

0.43

4.5

330

3510

T

N,N-Dimethylformamide

C3H7NO

-61

153

0.944

38.25

0.161

-1.01

0.76

0.91

0.91

6.4

270

 

Nitromethane

CH3NO2

-29

101

1.382

37.27

0.064

-0.33

0.54

0.64

0.65

5.3

380

1020

 

n-Propanol

CH3CH2CH2OH

-127

  97

0.804

20.8

0.757

 0.25

0.60

0.82

2.30

4.3

210

T

Pentane

C5H12

-130

 36

0.626

1.84

 

 3.39

0.00*

0

0.24

0

195

 

M, T?

Pyridine

C5H5N

42

116

0.982

12.4

 

 0.70

 

0.71

0.94

5.3

330

M, T?

Tetrahydrofuran

C4H8O

-108

  66

0.889

7.52

0.047

 0.46

0.35

0.45

0.55

4.2

220

T

Toluene

C6H5CH3

-95

111

0.867

2.38

0.040

 2.73

0.23

0.29

0.59

2.4

286

0.0516

T

Water

H2O

  0

100

1.000

78.4

0.123

 

0.82

1.29

 1.00 

10.2

191

 

 

Legend:

* = defined values

tan
δ= loss tangent at 2.45 GHz (Microwave)

Log Kow= partition coefficient of unionized compound between n-octanol and water

eo = eluotropic strength  (solvent strength parameter)

P  = polarity index according to Synder

η(cp) = viscosity of the compound at 20 oC

UV Cutoff = lower limit for the measurement in the UV-Vis spectrum

The solubility is given in g of solute in 100 g water. The superscript indicates the temperature it was recorded.


Health hazards: Corr=corrosive, C=carcinogen, M=mutagenic, T=teratogenic


General Rules:

1. Halogenated solvents possess a higher density than non-halogenated solvents.

2. Halogenated solvents are not flammable.

3. Ethers such as tetrahydrofuran and diethyl ether tend to form (explosive) peroxides. Thus, they can only be used for a limited time. Be careful when using them.

4. Low boiling solvents i.e., diethyl ether, dichloromethane, etc. can build up a significant pressure when used in extractions. Make sure that the solutions that you are using are at room temperature or below.