This quarter, the students will perform Extra Credit Project 2 (Microwave Synthesis of Phenytoin). The prelab questions below refer to this project: The pre-lab questions (due together with the rest of the prelab by Friday, April 24, 2015 at 4:30 pm in the instructor's office) :

1. Why can this reaction be considered an example for Green Chemistry? (Hint: It might be useful to read the corresponding chapter in the SKR)

2. Why is it crucial for the success of the reaction that the reactants are ground together properly?

3. Which precautions does the student have to take (i) before the reaction   (ii) during the reaction   (iii) after the reaction in the microwave?

4. Upon cooling to room temperature, the reaction mixture is treated with 95 % ethanol. Which purpose does this serve? Which portion of the mixture is the student interested in here?

5. Hydrochloric acid is added to the filtrate obtained in 4.. Which purpose does this serve?

6. The student submits a sample for GC/MS analysis. Which solvent and which concentration is appropriate here?

7. How many signals are observed in the ¹H-NMR spectrum of the compound?

Notes:

1. As part of the prelab the student has to include a proper infrared spectrum and mass spectrum which has pertinent peaks labeled.

2. The experiment will be carried out during the week of May 5, 2015 through May 7, 2015 during the student's regular meeting.

3. The formal report will be due by May 15, 2015 at 4:30 pm in YH 3077E as hardcopy and by 5:00 pm on the same day on turnitin.com (Course ID: 9622525, Password: Chem30BL).