Illustrated Glossary of Organic Chemistry

Methoxide (methoxide ion; MeO^-): CH₃O^-; the conjugate base of methanol. A strong base (frequently used in E2 and enolate reactions) and a good nucleophile.

Molecular structure of methoxide ion.


Sodium methoxide in an E2 reaction.


Potassium methoxide in a Williamson ether synthesis (an S_N2 reaction).